
Non-protein-coding DNA sequences that are interspersed
within genes are called introns.
Introns are transcribed into mRNA along with coding
sequences, but must be removed before the mRNA can be used
for protein synthesis.
Exons are
protein-coding DNA sequences within genes.
The newly
coined term exome refers to the protein-coding DNA
sequences of the genome.
The exome constitutes about
1.5% of the human genome.
Because the exome contains all the protein
information about the genome, it is considered the most
important and most interpretable part of the genome.
Whereas 3 billion bases must be sequenced to yield a
complete genome sequence, only about 45 million bases need
to be sequenced to yield a person's exome.