Personal Genome Project Study Guide
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Part I: Genetic Material

Part II: Gene Transmission

Part III: Gene Expression

Part IV: Genetic Regulation

Part V: Genetics and Society

Part VI: Project Literacy

 

 

 

 

 

  Part III: Gene Expression
Lesson 7: Coding for Proteins
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Lesson 7 Practice Test

Non-protein-coding DNA sequences that are interspersed within genes are called introns.  Introns are transcribed into mRNA along with coding sequences, but must be removed before the mRNA can be used for protein synthesis.

Exons are protein-coding DNA sequences within genes.

The newly coined term exome refers to the protein-coding DNA sequences of the genome.  The exome constitutes about  1.5% of the human genome.  Because the exome contains all the protein information about the genome, it is considered the most important and most interpretable part of the genome.  Whereas 3 billion bases must be sequenced to yield a complete genome sequence, only about 45 million bases need to be sequenced to yield a person's exome.

 

 

 

Intron removal from mRNA

 

Introns and exons in genes